Welcome to Babu Lab Welcome to Babu Lab Department of Biochemistry University of Regina University of Regina











  • Welcome to the Babu Lab


    The Babu Lab is located at the newly constructed Research and Innovation Centre at the University of Regina Campus, Saskatchewan.

    The primary research focus of Babu’s laboratory is to characterize the comprehensive networks of physical (protein-protein) and functional (gene-gene, or genetic) interaction maps that underlie major cellular processes in prokaryotes and eukaryotes. The resulting physical and functional interaction maps will be integrated to organize protein complexes into higher order pathways that mediate and coordinate major bioprocesses in the cell. The knowledge gained from these interaction maps will not only enhance the fundamental understanding of the molecular wiring of proteins in the cells, but also provide mechanistic insights that could be potentially exploited for identifying novel therapeutic targets as well as therapies for the treatment of human diseases.


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    Intergrated biological network of E.coli functional modules
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    Structural analysis of the E. coli binary interactome
    02
    Differential Essentiality Map
    02
    Autophagy interaction network
    02
    Yeast Cell
    01
    Yeast Cell Envelope
    02
    Yeast Membrane Proteins Interaction Network
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    Overview of E. coli conjugation
    03
    Genetic / Functional redundancy between parallel pathways
    03
    Buffering or synthetic genetic interaction patterns predict pathways
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    Overview of the ESGA Process
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    Three Basic Types of Genetic Interactions
    03
    Clustering of Genetic Interaction Profiles
    03
    E. coli Cell-Envelope
    03
    Conservation of envelope bioprocess across bacterial species
    01
    Colanic acid, Cell Wall & LPS Pathway Cross-Talk
    02
    Global Functional Atlas of E. coli Encompassing Previously Uncharacterized Proteins

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Department of BioChemistry, Room 232, Research and Innovation Centre University of Regina, Regina, Saskatchewan S4S 0A2
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